Bioactive Lipid Mediators
-15%
portes grátis
Bioactive Lipid Mediators
Current Reviews and Protocols
Murakami, Makoto; Yokomizo, Takehiko
Springer Verlag, Japan
11/2015
426
Dura
Inglês
9784431556688
15 a 20 dias
8535
Descrição não disponível.
PART I ENZYMES AND RECEPTORS FOR LIPID MEDIATORS.- 1 Lysophospholipid Acyltransferases.- 2 Phospholipase A2.- 3 Prostaglandin Terminal Synthases as Novel Drug Targets.- 4 Pathophysiological Roles of Prostanoid Receptors in the Central Nervous System.- 5 Lipoxygenases: A Chronological Perspective on the Synthesis of S and R Fatty Acid Hydroperoxides.- 6 Leukotriene B4 Receptors.- 7 Platelet-Activating Factor (PAF) in Infectious Diseases.- 8 Lysophospholipid Mediators: Their Receptorsand Synthetic Pathways.- 9 Sphingolipid Metabolism via Sphingosine 1-Phosphate and Its Role in Physiology, Pathology, and Nutrition.- 10 Fatty Acids Receptors.- 11 Omega-3 Fatty Acid Metabolism and Regulation of Inflammation.- PART II LIPID MEDIATORS IN DROSOPHILA AND ZEBRAFISH.- 12 Membrane Lipid Transporters in Drosophila melanogaster.- 13 Drosophila: A Model for Studying Prostaglandin Signaling.- 14 Zebrafish as a Model Animal for Studying Lysophosphatidic Acid Signaling.- 15 Sphingosine 1-Phosphate Signaling via Transporters in Zebrafish and Mice.- PART III LIPID MEDIATORS AND DISEASES.- 16 Lipid Mediator LPA-Induced Demyelination and Self-Amplification of LPA Biosynthesis in Chronic Pain Memory Mechanisms.- 17 Vascular Endothelial S1P2 Receptor Limits Tumor Angiogenesis and Hyperpermeability.- 18 Roles of Prostaglandins in Regulation of Pathological Angiogenesis and Lymphangiogenesis.- 19 Eicosanoids and Aortic Aneurysm.- 20 Cysteinyl Leukotrienes and Disease.- 21 Lipid Mediators and Skin Diseases.- 22 Roles and Actions of Arachidonic Acid-Derived Bioactive Lipids in Stress-Related Behaviors.- PART IV PROTOCOLS FOR ANALYZING LIPID MEDIATORS.- 23 Basic Techniques for Lipid Extraction from Tissues and Cells.- 24 Comprehensive Analysis of Eicosanoids.- 25 Mass Spectrometric Analysis of Phospholipids by Target Discovery Approach.- 26 Determination of Sphingolipids by LC-MS/MS.- 27 Lipid Machinery Investigation Using MALDI Imaging Mass Spectrometry. 28 Measuring Activationof Lipid G Protein-Coupled Receptors Using the TGF-? Shedding Assay.- 29 A Novel Anti-FLAG Monoclonal Antibody is Useful to Study GPCRs.- Index.
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Eicosanoid;Leukotriene;Lipid research model animal;Lipid research protocol;Lipidomics;Lysophospholipid;Mass spectrometry;New drug target;Prostaglandin;?3 polyunsaturated fatty acid
PART I ENZYMES AND RECEPTORS FOR LIPID MEDIATORS.- 1 Lysophospholipid Acyltransferases.- 2 Phospholipase A2.- 3 Prostaglandin Terminal Synthases as Novel Drug Targets.- 4 Pathophysiological Roles of Prostanoid Receptors in the Central Nervous System.- 5 Lipoxygenases: A Chronological Perspective on the Synthesis of S and R Fatty Acid Hydroperoxides.- 6 Leukotriene B4 Receptors.- 7 Platelet-Activating Factor (PAF) in Infectious Diseases.- 8 Lysophospholipid Mediators: Their Receptorsand Synthetic Pathways.- 9 Sphingolipid Metabolism via Sphingosine 1-Phosphate and Its Role in Physiology, Pathology, and Nutrition.- 10 Fatty Acids Receptors.- 11 Omega-3 Fatty Acid Metabolism and Regulation of Inflammation.- PART II LIPID MEDIATORS IN DROSOPHILA AND ZEBRAFISH.- 12 Membrane Lipid Transporters in Drosophila melanogaster.- 13 Drosophila: A Model for Studying Prostaglandin Signaling.- 14 Zebrafish as a Model Animal for Studying Lysophosphatidic Acid Signaling.- 15 Sphingosine 1-Phosphate Signaling via Transporters in Zebrafish and Mice.- PART III LIPID MEDIATORS AND DISEASES.- 16 Lipid Mediator LPA-Induced Demyelination and Self-Amplification of LPA Biosynthesis in Chronic Pain Memory Mechanisms.- 17 Vascular Endothelial S1P2 Receptor Limits Tumor Angiogenesis and Hyperpermeability.- 18 Roles of Prostaglandins in Regulation of Pathological Angiogenesis and Lymphangiogenesis.- 19 Eicosanoids and Aortic Aneurysm.- 20 Cysteinyl Leukotrienes and Disease.- 21 Lipid Mediators and Skin Diseases.- 22 Roles and Actions of Arachidonic Acid-Derived Bioactive Lipids in Stress-Related Behaviors.- PART IV PROTOCOLS FOR ANALYZING LIPID MEDIATORS.- 23 Basic Techniques for Lipid Extraction from Tissues and Cells.- 24 Comprehensive Analysis of Eicosanoids.- 25 Mass Spectrometric Analysis of Phospholipids by Target Discovery Approach.- 26 Determination of Sphingolipids by LC-MS/MS.- 27 Lipid Machinery Investigation Using MALDI Imaging Mass Spectrometry. 28 Measuring Activationof Lipid G Protein-Coupled Receptors Using the TGF-? Shedding Assay.- 29 A Novel Anti-FLAG Monoclonal Antibody is Useful to Study GPCRs.- Index.
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