Essentials of Lung Transplantation

Essentials of Lung Transplantation

Bos, Saskia; Fisher, Andrew J.; Vos, Robin

Taylor & Francis Ltd

03/2025

194

Dura

9781032559568

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1. Lung transplantation. 1.1 Lung transplantation: where are we today? 1.2 Ethical considerations regarding lung transplantation. 2. Pre-transplant. 2.1 Indications for lung transplantation. 2.2 How to select a good recipient? 2.3 A patient on the waiting list: how to manage and when to transplant. 2.4 How are organs allocated? 2.5 How to select a good donor? 3. Peri-transplant. 3.1 Type of lung transplantation. 3.2 Type of procedure. 3.3 ECMO, cardiopulmonary bypass and off-pump. 3.4 What is ischaemia time? 3.5 Should we use ex vivo lung perfusion? 3.6 To induce or not? 4. Post-transplant medication and follow-up. 4.1 Maintenance immunosuppression. 4.2 Prophylaxis. 4.3 What to expect after lung transplantation?. 4.4 General follow-up post-transplant. 4.5 Surgery in lung transplant patients. 4.6 Pregnancy and lung transplantation. 4.7 Medication interactions. 5. General post-operative complications and primary graft dysfunction . 5.1Pleural complications. 5.2 Ischaemic airway complications and fistulas. 5.3 Other post-operative complications. 5.4 Primary graft dysfunction (PGD). 6. Post-transplant complications: rejection. 6.1 Introduction acute and chronic rejection. 6.2 Hyperacute rejection: does it still exist?.6.3 Acute cellular rejection (ACR). 6.4 Donor specific antibodies (DSA): what and how to interpret?6.5 Antibody-mediated rejection (AMR). 6.6 Chronic rejection: chronic lung allograft dysfunction (CLAD). 6.7 Bronchiolitis obliterans syndrome (BOS). 6.8 Restrictive allograft syndrome (RAS). 6.9 Biomarkers and future therapies. 7. Other common post-transplant complications. 7.1 Infections. 7.2 Malignancies. 7.3 Kidney dysfunction. 7.4Metabolic complications and cardiovascular disease. 7.5 Reflux and other gastrointestinal issues: why it matters. 7.6 PRES: posterior reversible encephalopathy syndrome. 8. Clinical cases. 1.3Clinical case: early post-operative evolution. 1.4 Clinical case: ACR, infection and CLAD . 1.5Clinical case: CMV infection. 1.6 Clinical case: PTLD
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Immunosuppression;Induction therapy;Post-transplant complications;Acute rejection;Antibody-mediated rejection;Chronic rejection